ISC Class 12 Biology Question Bank 2026-27

A complete question bank for ISC Class XII Biology students, covering all 13 chapters of the ISC syllabus across all five units. Contains 55+ questions per chapter with detailed model answers, 28 original biology diagrams, and image-based questions throughout.

Coverage — All 13 Chapters Across 5 Units

Unit I — Reproduction: Chapter 1: Sexual Reproduction in Flowering Plants (Microsporogenesis, Megasporogenesis, Pollination, Double Fertilisation, Apomixis, Polyembryony), Chapter 2: Human Reproduction (Spermatogenesis, Oogenesis, Fertilisation, Implantation, Placenta, Parturition), Chapter 3: Reproductive Health (STIs, Contraception, MTP, ART — IVF, GIFT, ICSI, PCPNDT Act)

Unit II — Genetics and Evolution: Chapter 4: Principles of Inheritance and Variation (Mendel's Laws, Linkage, Sex Determination, Chromosomal Disorders, Pedigree Analysis), Chapter 5: Molecular Basis of Inheritance (DNA Structure, Replication, Transcription, Translation, Lac Operon, HGP, DNA Fingerprinting), Chapter 6: Evolution (Hardy-Weinberg, Natural Selection, Speciation, Adaptive Radiation, Human Evolution)

Unit III — Biology and Human Welfare: Chapter 7: Human Health and Diseases (Immunity, Vaccination, Malaria, AIDS, Cancer, Drug Abuse), Chapter 8: Microbes in Human Welfare (Industrial Products, Sewage Treatment, Biofertilisers, Biocontrol Agents)

Unit IV — Biotechnology: Chapter 9: Biotechnology — Principles and Processes (rDNA Technology, Restriction Enzymes, PCR, Gel Electrophoresis, Bioreactors), Chapter 10: Biotechnology and its Applications (Recombinant Insulin, GM Crops, Gene Therapy, Biopiracy, GEAC)

Unit V — Ecology and Environment: Chapter 11: Organisms and Populations (Population Growth, r and K Selection, Species Interactions), Chapter 12: Ecosystem (Energy Flow, Ecological Pyramids, Nutrient Cycles, Decomposition), Chapter 13: Biodiversity and Conservation (IUCN Categories, Hotspots, In-situ/Ex-situ Conservation, Project Tiger, CITES)

Structure of Each Chapter

Every chapter is divided into five sections: Section A — 15 MCQs (including 3–5 image-based questions referencing original diagrams), Section B — Short Answer I (2 marks), Section C — Short Answer II (3 marks), Section D — Long Answer (5 marks), and Section E — 15–20 additional practice questions. Each chapter closes with an Examiner's Tip box highlighting frequently tested topics.

Diagrams and Visual Content

The book contains 28 original biology diagrams embedded within questions, covering DNA double helix, PCR cycle, gel electrophoresis, Punnett squares, pedigree charts, malaria life cycle, antibody structure, lac operon, ecosystem energy flow, nutrient cycles, population growth curves, and more. Image-based questions appear in MCQ sections throughout.

Additional Note

The preface notes that the ISC Class 12 Biology syllabus overlaps significantly with the NEET Biology syllabus, making this resource potentially useful for students preparing for both.

Disclaimer

This is an independent educational resource and is not affiliated with, endorsed by, or connected to the ISC board, CISCE, or any government body. Questions are designed to be representative of the ISC examination pattern but are not official board materials.